There are various types or species of Streptococci ("strep") bacteria. The two groups briefly discussed here are from group A Streptococcus pyogenes GAS and group B Streptococcus agalactiae GBS. Nonpathogenic forms of strep bacteria normally live on the skin, inside the mouth, nose, throat, and inside the intestines. However, streptococcal bacteria can cause different types of noninvasive and invasive illnesses, directly or indirectly, when they enter the bloodstream. This may cause an array of infections or secondary complications such as bacteremia, cellulitis, endocarditis, erysipelas, glomerulonephritis, impetigo, meningitis, necrotizing fasciitis, pneumonia, rheumatic fever, scarlet fever, strep throat, and streptococcal toxic shock syndrome. The term streptococcus, is often confused with Staphylococcus, or "staph", or "staph aureus". The Staphylococcus aureus species that affects man mirrors the strep range of diseases in many cases, but is especially known for causing skin infections such as cellulitis, and is most notorious for causing food poisoning.
Streptococcal bacteria are not exclusive to all the types of diseases listed below. For example, endocarditis can also be caused by fungi or other germs. Another example is pneumonia, that may be caused by viruses, parasites, fungi, or noninfectious lung diseases. Also, streptococcal bacteria can be indirectly responsible for actual tissue damage or complications that occur during a bout of infection. An example is rheumatic fever and the body's immune response to infection that ultimately causes lasting damage to tissue.
Bacteremia, sometimes referred to as "blood poisoning", is the condition of having viable bacteria in the bloodstream. Typically, bacteria enter the blood through an injury such as a cut, puncture wound, burn, skin abrasion, through dental procedures, or surgical injection. The natural barriers within the body's immune system tend to stave off serious infection, and for the most part, it is considered clinically benign. Serious systemic infection can occur if left untreated especially in cases that involve a high volume of viable bacteria in the bloodstream that accumulate in certain tissues or organs, through extensive bacterial toxins, or for certain high risk individuals. Examples of high risk individuals may include people with heart valve defects, artificial joints, and having a weak immune system. Bacteremia can lead to sepsis and other serious infections if not monitored and treated effectively.
Cellulitis is a skin infection that can affect any part of the body and is caused by streptococcus, staphylococcus, and other types of bacteria. Early stages include symptoms such as red and tender areas that feel warm and may become swollen. Other symptoms may include pain in the affected area, fever, hair loss, nausea, sweating, swollen glands and more. It often occurs in regions of the skin that have been previously damaged. Cellulitis can also occur for individuals with a weak immune system, diabetes and other conditions. Antibiotics are normally prescribed in minor cases and may take 7 - 10 days of treatment. More severe cases may require hospitalization. To learn more visit U.S. National Library of Medicine.
Endocarditis is an infection of the endocardium and heart valves caused by bacteria such as streptococcus, fungi, or other germs. The highest risk individuals tend to have prior heart defects, but aggressive forms of bacteria may infect a healthy heart. With endocarditis, clumps of bacteria and blood clots (vegetations) accumulate on the surface of heart valves causing damage and leakage ultimately leading to heart failure. Poor dental hygiene and unhealthy teeth and gums increase your risk of endocarditis. Most people who are immediately treated with the proper antibiotics recover. Learn more about endocarditis at U.S. DHHS: National Heart Lung and Blood Institute.
Erysipelas is a bacterial infection similar to cellulitis but tends to be less raised, and may appear at several separate locations on the body at the same time. Erysipelas is a potentially dangerous infection especially to children and the elderly. Left untreated, the bacteria can spread to the blood and cause infection to deeper tissues and vital organs like the heart. Erysipelas infections are commonly visible on the facial area such as the bridge of the nose, cheeks, and around eyes. Most people immediately treated with the proper antibiotics recover.
Glomerulonephritis, sometimes referred to as "nephritis", is an infection of the glomeruli. The glomerulus are tiny, tubular tufts of capillaries in the kidneys that filter blood by removing waste.
When infected, the filtering capabilities are greatly hindered resulting in protein and red blood cells passing into urine. This loss of protein in the bloodstream may result in endema (fluid buildup) throughout the body. This condition is called nephrotic syndrome. Left untreated, chronic glomerulonephritis symptoms may have a slow onset of symptoms, may come-and-go for months at a time, but ultimately can lead to kidney failure. Acute cases will produce extreme symptoms that require immediate medical attention.
Impetigo is a bacterial infection that is highly contagious and usually found in children. It usually begins with a reddening of the skin typically around the nose and mouth. This is followed by tiny bumps or blisters that are sometimes hard to distinguish. Complications may include inflammation of the kidneys, blood infection, and lymphatic damage if not treated. Care should be taken not to touch the infected areas to avoid spreading the infection to yourself or others. Children with impetigo should be separated from other children until the infection is treated. It's recommended to wash all linens and clothing frequently until the infection is eradicated. Personal hygiene items, like the child's soap, should be kept away from others. Talk to a doctor immediately in order to discuss treatment options.
Bacterial meningitis is a serious, potentially life threatening infection of the triple layer of protective tissue which envelops the central nervous system. These membranes are collectively called meninges. The three layers of the meninges are called dura mater, arachnoid, and pia mater [see illustration]. Approximately 80 percent of all meningitis cases are identified as acute bacterial meningitis. Most cases of meningitis can be treated and people will see full recovery. If left untreated, more serious complications are likely to occur such as hearing loss, brain damage, and other brain disorders. Infants are at higher risk for bacterial meningitis as well as people with weakened immune systems. The hallmark symptoms include sudden onset of headache, fever and a stiff neck. Other symptoms may include nausea, vomiting, photophobia (a sensitivity to light), bulging fontanelle (in infants), abnormal reflex response, and confusion. The more severe cases of untreated bacterial meningitis can lead to seizures, coma, and death. Antibiotics can help prevent severe illness and reduce the spread of infection. Sometimes the exact causes of certain meningitis cases remain a mystery. Other times infections can occur due to a weakened immune system, from pneumococcal pneumonia, through alcohol abuse, serious blood infection, chronic nose and ear infections, brain or spinal surgery complications, or from head injury.
Necrotizing Fasciitis (NF)
Necrotizing Fasciitis (NF) is medical emergency also known as flesh-eating disease or flesh-eating bacteria syndrome. Necrotizing fasciitis spreads quickly, destroying (necrotizing) the body's soft tissue and fascia (a structure of connective tissue covering muscle). Necrotizing fasciitis is very rare but it's a serious condition because of the toxic properties and enzymes produced by the bacteria. These toxins and enzymes rapidly destroy tissue and can lead to secondary systemic shock resulting in respiratory failure, heart failure, and renal failure. Death occurs in about 1/4 of acute cases according to the CDC but this number may be higher according to the NNFF. Necrotizing fasciitis bacteria can enter a wound, insect bite, wounds that contact sea water, raw seafood such as oysters or crabs, from C-section or vaginal birth, intestinal wounds, muscle strain or bruise (even if internal), a burn, a cut, or just about any type of trauma. However, spontaneous cases where no apparent injury can be found, are also reported according to the National Necrotizing Fasciitis Foundation. Necrotizing fasciitis can be spread from person-to-person through close contact usually by touching an open wound, respiratory droplets, or direct contact with secretions of someone carrying Strep A. Prompt diagnosis is crucial to decrease the risk of disfigurement or death.
Pneumonia - Streptococcus pneumoniae
Bacterial pneumonia can be caused by streptococcus pneumoniae. Pneumonia is an infection of the lungs with associated swelling and fluid inside the lungs. Symptoms may include fever, chills, frequent cough, cold or flu symptoms, fatigue, shortness of breath, and chest pain. Invasive pneumococcal diseases also include bacteremia, otitis media, meningitis, acute sinusitis, sepsis, osteomyelitis, septic arthritis, endocarditis, peritonitis, pericarditis, cellulitis, and brain abscess. Treatment of pneumonia often includes antibiotics. A doctor determines whether an x-ray is needed. Hospitalization may be required depending on the severity of the infection. Lesser infections, sometimes referred to as Walking pneumonia, have mild symptoms and may only require staying home from school, work, and bed rest.
Rheumatic fever, or Acute rheumatic fever (ARF), is an inflammation that develops after an infection with group A streptococcus bacteria such as from complications related to untreated strep throat or scarlet fever. This disease can attack connective tissue of the heart, skin, joints, and brain. It's believed that long-lasting damage, especially to heart valves, stems from the body's own immune system response to the infection caused by the bacteria and not from the bacteria itself. Rheumatic fever most commonly affects children up to the age of 15 years. The strains of streptococcal bacteria that cause rheumatic fever are rare in the United States, but it remains a common disease worldwide.
Scarlet fever, or scarlatina, is an infection caused by the toxins of streptococcal bacteria and produces a rough, scarlet-colored rash and is typically found in children 4-12 years of age. Symptoms include the already mentioned skin rash, plus any of the following: fever, sore throat, painful swallowing, whitish and/or swollen tongue, red and/or sore tonsils, chills, vomiting, and abdominal pain. Scarlet fever is treatable with antibiotics and may prevent further complications. Complications are more likely if scarlet fever goes untreated and may include rheumatic fever, poststreptococcal glomerulonephritis, ear infections, skin infections, abscesses of the throat, pneumonia, and arthritis.
Strep Throat - Streptococcus pyogenes
Strep throat is a contagious bacterial infection that causes pharyngitis, a soreness of the throat and is spread through close contact. Common symptoms include an initial tickling of the throat or irritation. This is generally followed by sore throat, swollen tonsils, fever, difficulty when swallowing, and enlarged lymph nodes. Another distinct symptom can be the absence of a cough while one or more of the symptoms described still exist. A doctor will typically perform a throat culture to help identify the bacteria. Treatment typically involves antibiotics. If left untreated, strep throat can lead to complications such as rheumatic fever.
Streptococcal Toxic Shock Syndrome [STSS]
Streptococcal Toxic Shock Syndrome STSS, or streptococcal TSS, is a severe infection associated with invasive or non-invasive group A streptococcal (streptococcus pyogenes) or a staphylococcus aureus infection. This rare illness is considered a medical emergency. Acute symptoms include shock, hypotension (low blood pressure), renal (kidney) impairment, coagulopathy (abnormality in the blood's ability to clot), adult acute respiratory distress syndrome, rash, local tissue destruction. Death occurs in up to 50-70% of people who develop streptococcal toxic shock syndrome. Initial symptoms may include fever. TSS is abrupt in onset and severe, and usually precedes tenderness or physical findings. The pain usually involves an extremity but may also mimic peritonitis, pelvic inflammatory disease, pneumonia, acute myocardial infarction, or pericarditis. Twenty percent of patients have an influenza-like syndrome characterized by fever, chills, myalgia, nausea, vomiting, and diarrhea. Infections may be spread person-to-person through large respiratory droplets (coughing or sneezing) or by direct contact. Treatment options vary depending on severity, location, and other factors. The CDC had a PDF listing clinical symptoms.
References and other recommended sites that are not already listed
Harvard Medical School Family Health Guide. Komaroff. P.497,530,531,695,697,810,879